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Sudden cardiac death: opportunities for prevention

Abstract

The evidence base for implantable cardioverter-defibrillator (ICD) therapy requires expansion of guidance/indications to allow UK physicians to treat a broader range of patients. The ICD clinical consultees to the National Institute for Health and Clinical Excellence (NICE) review current guidance/guidelines, explain the evidence base, and suggest a UK ICD implantation strategy

  • ATP, antitachycardia pacing
  • AVID, antiarrhythmics versus implantable defibrillators study
  • CABG Patch, coronary artery bypass graft patch trial
  • CARE-HF, cardiac resynchronization-heart failure study
  • CASH, cardiac arrest study Hamburg
  • CIDS, Canadian implantable defibrillator study
  • CRT, cardiac resynchronisation therapy
  • DAVID, dual chamber and VVI implantable defibrillator trial
  • DINAMIT, defibrillator in acute myocardial infarction trial
  • EF, ejection fraction
  • EPS, electrophysiological study
  • ICD, implantable cardioverter-defibrillator
  • MADIT I, multicenter automatic defibrillator implantation trial
  • MADIT II, multicenter automatic defibrillator implantation trial II
  • MI, myocardial infarction
  • MUSTT, multicenter unsustained tachycardia trial
  • NHS, National Health Service
  • NICE, National Institute for Health and Clinical Excellence
  • NYHA, New York Heart Association
  • QoL, quality of life
  • SCD, sudden cardiac death
  • SCD HeFT, sudden cardiac death in heart failure trial
  • VF, ventricular fibrillation
  • VT, ventricular tachycardia
  • cost efficacy
  • implantable cardioverter-defibrillator
  • ICD
  • guidelines
  • sudden cardiac death

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